Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors Academic Article uri icon

Overview

MeSH Major

  • Angiogenesis Inhibitors
  • Neoplasms
  • Recombinant Fusion Proteins

abstract

  • IV VEGF Trap was well tolerated at the dose levels tested. Pharmacodynamic and pharmacokinetic markers were indicative of VEGF blockade.

publication date

  • January 10, 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2815710

Digital Object Identifier (DOI)

  • 10.1200/JCO.2009.22.9237

PubMed ID

  • 19949018

Additional Document Info

start page

  • 207

end page

  • 14

volume

  • 28

number

  • 2