Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase- dependent nitric oxide generation Academic Article uri icon

Overview

MeSH Major

  • Hypertension, Pulmonary
  • Hypoxia
  • Nitric Oxide
  • Sodium Nitrite
  • Xanthine Dehydrogenase

abstract

  • These studies reveal a potent effect of inhaled nitrite that limits pathological pulmonary arterial hypertrophy and cellular proliferation in the setting of experimental pulmonary arterial hypertension.

publication date

  • January 2010

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/CIRCULATIONAHA.109.891077

PubMed ID

  • 20026772

Additional Document Info

start page

  • 98

end page

  • 109

volume

  • 121

number

  • 1