Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Flavonoids
  • Fluorouracil
  • Leucovorin
  • Neoplasms
  • Organoplatinum Compounds
  • Piperidines

abstract

  • Flavopiridol with FOLFOX is a safe and tolerable regimen. Promising clinical activity was seen across tumor types. Encouraging results in the platinum-refractory germ cell tumor population has prompted a phase II trial that is currently open for accrual.

publication date

  • December 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2787644

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-09-1502

PubMed ID

  • 19934304

Additional Document Info

start page

  • 7405

end page

  • 11

volume

  • 15

number

  • 23