Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes Academic Article uri icon

Overview

MeSH Major

  • Anti-Inflammatory Agents, Non-Steroidal
  • Dendritic Cells
  • Immunoglobulin G
  • Interleukin-17
  • Myeloid Cells
  • Psoriasis
  • Receptors, Tumor Necrosis Factor
  • T-Lymphocytes, Helper-Inducer

abstract

  • Although both responders and nonresponders to etanercept inactivated sepsis cascade cytokines, response to etanercept is dependent on inactivation of myeloid dendritic cell genes and inactivation of the T(H)17 immune response.

publication date

  • November 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2852188

Digital Object Identifier (DOI)

  • 10.1016/j.jaci.2009.08.046

PubMed ID

  • 19895991

Additional Document Info

start page

  • 1022

end page

  • 10.e1-395

volume

  • 124

number

  • 5