Impairment of intracerebral arteriole dilation responses after subarachnoid hemorrhage: Laboratory investigation Academic Article uri icon

Overview

MeSH Major

  • Cerebrovascular Circulation
  • Subarachnoid Hemorrhage
  • Vasodilation

abstract

  • Subarachnoid hemorrhage led to a persistent impairment of endothelium-dependent dilation and a transient attenuation of vascular smooth muscle-dependent dilation responses to adenosine. Impairment of NO-mediated dilation occurred when the response to cGMP was intact, suggesting a change in cGMP levels rather than an alteration in intracellular mechanisms downstream from cGMP.

publication date

  • December 8, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.3171/2009.3.JNS096

PubMed ID

  • 19408973

Additional Document Info

start page

  • 1008

end page

  • 13

volume

  • 111

number

  • 5