Lack of effect of stimulant combination with second-generation antipsychotics on weight gain, metabolic changes, prolactin levels, and sedation in youth with clinically relevant aggression or oppositionality Academic Article uri icon

Overview

MeSH Major

  • Antipsychotic Agents
  • Attention Deficit Disorder with Hyperactivity
  • Central Nervous System Stimulants
  • Mental Disorders

abstract

  • In contrast to guidelines, stimulant use did not precede or accompany antipsychotic use during the current episode of aggression/oppositionality in almost half of those youths who had aggressive/oppositional behavior and a DSM-IV diagnosis of ADHD. At the clinically prescribed doses, stimulant co-treatment of SGAs did not seem to significantly reduce antipsychotic effects on body composition, metabolic parameters, prolactin, sedation, and broad efficacy.

publication date

  • October 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2830212

Digital Object Identifier (DOI)

  • 10.1089/cap.2009.0051

PubMed ID

  • 19877981

Additional Document Info

start page

  • 563

end page

  • 73

volume

  • 19

number

  • 5