Update: prostate cancer early detection clinical practice guidelines. Academic Article uri icon


MeSH Major

  • Prostatic Neoplasms


  • Histopathologic analysis of a biopsy specimen of the prostate, examined to ascertain the presence of malignancy, can result in 4 possible diagnostic scenarios: (1) prostate cancer, (2) no evidence of cancer, (3) high-grade prostatic intraepithelial neoplasia, and (4) atypical small-gland proliferation suggestive of malignancy but not diagnostic. Until new studies provide a better method for selecting patients to undergo rebiopsy, patients diagnosed with high-grade prostatic intraepithelial neoplasia from a single core biopsy should undergo rebiopsy. A diagnosis of atypical glands suggestive of malignancy indicates that a rebiopsy should be performed because the chances of finding an invasive carcinoma are high.

publication date

  • January 2003



  • Academic Article



  • eng

PubMed ID

  • 19795576

Additional Document Info

start page

  • S57

end page

  • 60


  • 1 Suppl 1