Correlation of enzyme-inducing anticonvulsant use with outcome of patients with glioblastoma Academic Article uri icon

Overview

MeSH Major

  • Anticonvulsants
  • Brain Neoplasms
  • Glioblastoma

abstract

  • Paradoxically, enzyme-inducing anticonvulsant (EIAC) use correlated with superior outcome of patients with glioblastoma. These results suggest that in comparative clinical trials testing agents metabolized by P450 microsomal enzymes, treatment arms may need stratification for the proportion of patients receiving EIAC.

publication date

  • October 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2764724

Digital Object Identifier (DOI)

  • 10.1212/WNL.0b013e3181bbfeca

PubMed ID

  • 19822870

Additional Document Info

start page

  • 1207

end page

  • 13

volume

  • 73

number

  • 15