Primary central nervous system lymphoma: Coming or going?
Central Nervous System Neoplasms
PCNSL is a rare disease, affecting about 1200 people each year in the United States. Its very name highlights its most unique feature: a diffuse, large B-cell lymphoma limited to the CNS. It may involve the brain, cerebrospinal fluid, spinal cord, or the eyes which are actually neural tissue. How does such a malignancy arise in the only organ system of the body that is devoid of lymph nodes and lymphatics?