Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors Academic Article uri icon

Overview

MeSH Major

  • Melanins
  • Radiation Tolerance

abstract

  • We propose that due to melanin's numerous aromatic oligomers containing multiple pi-electron system, a generated Compton recoil electron gradually loses energy while passing through the pigment, until its energy is sufficiently low that it can be trapped by stable free radicals present in the pigment. Controlled dissipation of high-energy recoil electrons by melanin prevents secondary ionizations and the generation of damaging free radical species.

publication date

  • September 30, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2749938

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0007229

PubMed ID

  • 19789711

Additional Document Info

start page

  • e7229

volume

  • 4

number

  • 9