Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol Academic Article uri icon

Overview

MeSH Major

  • Cell Cycle Proteins
  • F-Box Proteins
  • Mutation
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
  • Receptor, Notch1
  • Ubiquitin-Protein Ligases

abstract

  • NOTCH1 and FBXW7 mutant-positive patients do not fare sufficiently well to warrant an individualized treatment approach in future studies.

publication date

  • September 10, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2744275

Digital Object Identifier (DOI)

  • 10.1200/JCO.2009.22.0996

PubMed ID

  • 19635999

Additional Document Info

start page

  • 4352

end page

  • 6

volume

  • 27

number

  • 26