Inhibition of the hedgehog pathway in advanced basal-cell carcinoma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Benzimidazoles
  • Carcinoma, Basal Cell
  • Hedgehog Proteins
  • Skin Neoplasms

abstract

  • GDC-0449, an orally active small molecule that targets the hedgehog pathway, appears to have antitumor activity in locally advanced or metastatic basal-cell carcinoma. (ClinicalTrials.gov number, NCT00607724.)

publication date

  • September 17, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa0905360

PubMed ID

  • 19726763

Additional Document Info

start page

  • 1164

end page

  • 72

volume

  • 361

number

  • 12