Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: A multicenter phase II trial Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Brain Neoplasms
  • Cranial Irradiation
  • Glioblastoma

abstract

  • Talampanel can be added to RT + TMZ without significant additional toxicity. The encouraging survival results in methylated and unmethylated patients suggest that blocking AMPA receptors may be a useful strategy in newly diagnosed glioblastoma.

publication date

  • September 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2734427

Digital Object Identifier (DOI)

  • 10.1200/JCO.2008.21.6895

PubMed ID

  • 19636006

Additional Document Info

start page

  • 4155

end page

  • 61

volume

  • 27

number

  • 25