PIK3CA mutation associates with improved outcome in breast cancer Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Mutation
  • Phosphatidylinositol 3-Kinases

abstract

  • This study defines the positive prognostic significance of PIK3CA mutations. This work is clinically relevant, as it will significantly affect the design of clinical trials planned for phosphatidylinositol 3-kinase-targeted therapy. Future work may define a population of older age breast cancer patients in whom therapy can be minimized.

publication date

  • August 15, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-09-0632

PubMed ID

  • 19671852

Additional Document Info

start page

  • 5049

end page

  • 59

volume

  • 15

number

  • 16