Corticorelin acetate injections for the treatment of peritumoral brain edema Review uri icon

Overview

MeSH Major

  • Brain Edema
  • Brain Neoplasms
  • Corticotropin-Releasing Hormone

abstract

  • Animal studies and a Phase I randomized trial have demonstrated that hCRF is well tolerated and effective in reducing PBE and its associated signs and symptoms. In addition, the effectiveness of this drug may be helpful in sparing the use of corticosteroid therapy in patients with brain tumors, with the results from several multicenter, randomized, placebo-controlled, Phase III clinical trials currently pending.

publication date

  • September 2009

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1517/13543780903190689

PubMed ID

  • 19678803

Additional Document Info

start page

  • 1413

end page

  • 9

volume

  • 18

number

  • 9