Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Antineoplastic Combined Chemotherapy Protocols
  • Cisplatin
  • Glutamates
  • Guanine
  • Mesothelioma
  • Pleural Neoplasms
  • Pneumonectomy

abstract

  • This multicenter trial showed that trimodality therapy with neoadjuvant pemetrexed plus cisplatin is feasible with a reasonable long-term survival rate, particularly for patients who completed all therapy. Radiologic response to chemotherapy, but not sex, histology, disease stage, or nodal status, was associated with improved survival.

publication date

  • June 20, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3646305

Digital Object Identifier (DOI)

  • 10.1200/JCO.2008.20.3943

PubMed ID

  • 19364962

Additional Document Info

start page

  • 3007

end page

  • 13

volume

  • 27

number

  • 18