Radiosynthesis of [131I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker - is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker? Academic Article uri icon

Overview

MeSH Major

  • Cell Hypoxia
  • Galactosides
  • Nitroimidazoles

abstract

  • Radiolabeled IAZGP produced via nucleophilic substitution is validated as an exogenous hypoxia marker. Specific activity does not appear to influence the in vivo hypoxia-mapping ability of the radiotracer.

publication date

  • July 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2837594

Digital Object Identifier (DOI)

  • 10.1016/j.nucmedbio.2009.03.002

PubMed ID

  • 19520288

Additional Document Info

start page

  • 477

end page

  • 87

volume

  • 36

number

  • 5