Hematopoietic stem cell transplantation in children with special reference to indian scenario
Hematopoietic stem cell transplantation (HSCT) has the capacity to achieve cure for many pediatric malignant and non-malignant diseases. Improved selection of donors using better HLA matching techniques, a wider selection of donor sources for unrelated transplants, newer regimens for immunosuppressive therapy and improved supportive care for complications related to the post transplant period have all led to improved outcomes. Clinicians should be aware of current indications for stem cell transplantation and patients should be referred early to transplant centers. In India, there is a need for capacity building in terms of developing transplant centers to cope with the large number of patients who need HSCT as well as training transplant physicians and nurses.