Treating human cancers with heat shock protein-peptide complexes: The road ahead Academic Article uri icon

Overview

MeSH Major

  • Heat-Shock Proteins
  • Neoplasms
  • Peptide Fragments

abstract

  • Immunization of human subjects with HSP-peptide complexes derived from autologous tumors mediates substantial clinical benefit in subjects with relatively early stage disease, consistent with results seen in animal models of cancer, and with an immunological mechanism of action. Additional clinical studies are essential for further development of this personalized medicine.

publication date

  • February 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1517/14712590802633918

PubMed ID

  • 19236248

Additional Document Info

start page

  • 179

end page

  • 86

volume

  • 9

number

  • 2