Average arterial input function for quantitative dynamic contrast enhanced magnetic resonance imaging of neck nodal metastases Academic Article uri icon

Overview

MeSH Major

  • Lymph Nodes
  • Lymphatic Metastasis
  • Oncolytic Viruses
  • Positron-Emission Tomography

abstract

  • We found no statistically significant overall bias in Ktrans or ve estimates derived from Avg-AIF, generated from a limited population, as compared with Ind-AIFs.However, further study is needed to determine whether calibration is needed across the range of Ktrans. The Avg-AIF obtained from a limited population may be used for pharmacokinetic modeling of DCE-MRI data in larger population studies with neck nodal metastases. Further validation of the Avg-AIF approach with a larger population and in multiple regions is desirable.

publication date

  • June 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2679707

Digital Object Identifier (DOI)

  • 10.1186/1756-6649-9-4

PubMed ID

  • 19351382

Additional Document Info

start page

  • 4

volume

  • 9

number

  • 1