Phosphorylated 4E-BP1 is associated with poor survival in melanoma Academic Article uri icon

Overview

MeSH Major

  • Adaptor Proteins, Signal Transducing
  • Melanoma
  • Phosphoproteins

abstract

  • Our data show that translation initiation is a common event in human metastatic melanoma and correlates with worse prognosis. Therefore, effective inhibition of the pathways responsible for 4E-BP1 phosphorylation should be considered to improve the treatment outcome of metastatic melanoma patients.

publication date

  • April 15, 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3995540

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-08-2336

PubMed ID

  • 19336517

Additional Document Info

start page

  • 2872

end page

  • 8

volume

  • 15

number

  • 8