Multiple sclerosis Chapter uri icon


MeSH Major

  • Alzheimer Disease
  • Cognition
  • Cytidine Diphosphate Choline
  • Dementia, Vascular
  • Nootropic Agents
  • Stroke


  • The neuroepidemiology of multiple sclerosis (MS) offers numerous interesting features including the peculiar distribution of this disease by age and sex, affecting predominantly women in young and middle-age adult age-groups, as well as a typical geographic pattern of occurrence with low prevalence in tropical regions and increasing prevalence in temperate regions. Although ethnic, racial, and genetic factors have been implicated, no definitive genetic markers have been identified and the mode of transmission remains unknown. Likewise, no single environmental factor has been demonstrated to cause MS. The recently proposed protective effect of sunlight exposure and vitamin D offers new hopes for the prevention and treatment of this potentially devastating condition. Finally, novel clinical trial methodologies have been proposed to determine in shorter and more efficient trials the effectiveness of future therapeutic agents in MS. © 2007 by Nova Science Publishers, Inc. All rights reserved.

publication date

  • December 2007



  • Book Chapter

Additional Document Info

start page

  • 557

end page

  • 572