Circulating prostate tumor cells detected by Reverse transcription-PCR in men with localized or castration-refractory prostate cancer: Concordance with CellSearch assay and association with bone metastases and with survival Academic Article uri icon

Overview

MeSH Major

  • Bone Neoplasms
  • Neoplastic Cells, Circulating
  • Orchiectomy
  • Prostatic Neoplasms
  • Reverse Transcriptase Polymerase Chain Reaction

abstract

  • Real-time RT-PCR assays of KLK mRNAs are highly concordant with CellSearch CTC results in patients with CRPC. KLK2/3-expressing CTCs are common in men with CRPC and bone metastases but are rare in patients with metastases diagnosed only in soft tissues and patients with localized cancer.

publication date

  • April 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2782624

Digital Object Identifier (DOI)

  • 10.1373/clinchem.2008.117952

PubMed ID

  • 19233911

Additional Document Info

start page

  • 765

end page

  • 73

volume

  • 55

number

  • 4