Relationship between recurrent vulvovaginal candidosis and immune mediators in vaginal fluid Academic Article uri icon

Overview

MeSH Major

  • Body Fluids
  • Candidiasis, Vulvovaginal
  • Dinoprostone
  • Immunoglobulin E
  • Interleukin-13
  • Interleukin-4
  • Interleukin-5
  • Vagina

abstract

  • These findings indicate that women with clinical vaginal symptoms have a localized vaginal immunosuppression which might be the cause of their symptoms. Greatly elevated vaginal PgE(2) levels can be a consequence of a localized allergic response. An allergic reaction to candida components may be the cause of the allergic response in those women with high levels of candida-specific IgE. In women with elevated PgE(2), treatment with an antihistamine or prostaglandin synthesis inhibitor might be beneficial.

publication date

  • May 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ejogrb.2009.01.010

PubMed ID

  • 19261373

Additional Document Info

start page

  • 59

end page

  • 63

volume

  • 144

number

  • 1