HLA-identical sibling compared with 8/8 matched and mismatched unrelated donor bone marrow transplant for chronic phase chronic myeloid leukemia Academic Article uri icon

Overview

MeSH Major

  • Bone Marrow Transplantation
  • Histocompatibility Antigens Class I
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive

abstract

  • In this homogeneous cohort of good risk patients with CML in CP1, 5-year overall survival and LFS after receipt of transplant from 8/8 allele-matched donors were modestly though significantly worse than those after receipt of transplant from MSDs. Additive adverse effects of multilocus mismatching are not well tolerated and should be avoided if possible.

publication date

  • April 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2668970

Digital Object Identifier (DOI)

  • 10.1200/JCO.2008.18.7740

PubMed ID

  • 19224849

Additional Document Info

start page

  • 1644

end page

  • 52

volume

  • 27

number

  • 10