Genetics of cardiac repolarization Article uri icon

Overview

MeSH Major

  • Action Potentials
  • Arrhythmias, Cardiac
  • Calcium
  • Calcium Signaling
  • Calmodulin
  • Voltage-Gated Sodium Channels

abstract

  • Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.

publication date

  • April 2009

Research

keywords

  • Article

Identity

PubMed ID

  • 19338079

Additional Document Info

start page

  • 388

end page

  • 9

volume

  • 41

number

  • 4