Utility of brain FDG-PET in primary CNS lymphoma. Academic Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Fluorodeoxyglucose F18
  • Lymphoma
  • Positron-Emission Tomography
  • Radiopharmaceuticals

abstract

  • 18Fluoro-deoxyglucose positron emission tomography (FDG-PET) imaging has been widely incorporated into the management of systemic non-Hodgkin lymphoma. However, its utility in primary central nervous system lymphoma (PCNSL) is unclear. We report 28 PCNSL patients who underwent brain FDG-PET to inform clinical management. Baseline PET imaging demonstrated hypermetabolism consistent with aggressive lymphoma in 75% (9/12) of patients. FDG-PET used for response assessment or the interpretation of nonspecific magnetic resonance imaging abnormalities showed hypermetabolism in 50% (10/20) of patients, which was important in guiding further management. This data suggests that FDG-PET imaging in PCNSL is useful and may have a role in response assessment.

publication date

  • November 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 19194366

Additional Document Info

start page

  • 818

end page

  • 20, 840

volume

  • 6

number

  • 11