Tumor vasculature-targeted delivery of tumor necrosis factor-α Academic Article uri icon

Overview

MeSH Major

  • Melanoma
  • Skin Neoplasms
  • Tumor Necrosis Factor-alpha

abstract

  • Targeted AAVP vectors can be used to deliver TNF-alpha specifically to tumor vasculature, potentially reducing its systemic toxicity. Because TNF-alpha is a promising antivascular agent that currently is limited by its toxicity, the current results suggest the potential for clinical translation of this strategy.

publication date

  • January 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.24001

PubMed ID

  • 19090007

Additional Document Info

start page

  • 128

end page

  • 39

volume

  • 115

number

  • 1