BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line Academic Article uri icon

Overview

MeSH Major

  • Carmustine
  • Cerebellar Neoplasms
  • Drug Resistance, Neoplasm
  • Medulloblastoma
  • Metallothionein

abstract

  • We demonstrate that resistance to BCNU may be a result of elevated levels of MTs which act by sequestering the drug's decomposition product(s).

publication date

  • March 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3635115

Digital Object Identifier (DOI)

  • 10.1007/s00280-008-0792-9

PubMed ID

  • 18633619

Additional Document Info

start page

  • 753

end page

  • 8

volume

  • 63

number

  • 4