Biopsy of the posterior interosseous nerve: A low morbidity method for assessment of peripheral nerve disorders
Diabetes Mellitus, Type 2
Peripheral Nervous System Diseases
A reduction in myelinated fibre density has previously been shown to be a clinically meaningful measure of neuropathy in diabetic patients. We demonstrate similar findings using the PIN biopsy. The PIN biopsy procedure fulfils the criteria for nerve biopsy and was well tolerated by the patients. It may be a possible alternative to sural nerve biopsy to allow for diagnosis of neuropathy.