Case 39-2008: A 51-year-old woman with splenomegaly and anemia
Anemia, Hemolytic, Autoimmune
Lymphoma, B-Cell, Marginal Zone
A 51-year-old woman was admitted to this hospital because of anemia and splenomegaly. Fatigue, night sweats, leg swelling, dyspnea on exertion, and early satiety had begun 2 months earlier. Examination and imaging studies disclosed a massively enlarged spleen, extending below the pelvic brim, with slightly enlarged intraabdominal lymph nodes; an IgM paraprotein was present in the serum, and the partial-thromboplastin time was prolonged. A diagnostic procedure was performed. Copyright © 2008 Massachusetts Medical Society.
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