The bivalent side of the nucleus accumbens. Academic Article uri icon

Overview

MeSH

  • Acoustic Stimulation
  • Adult
  • Brain Mapping
  • Female
  • Humans
  • Male

MeSH Major

  • Auditory Perception
  • Motivation
  • Nucleus Accumbens
  • Reward

abstract

  • An increasing body of evidence suggests that the nucleus accumbens (NAcc) is engaged in both incentive reward processes and in adaptive responses to conditioned and unconditioned aversive stimuli. Yet, it has been argued that NAcc activation to aversive stimuli may be a consequence of the rewarding effects of their termination, i.e., relief. To address this question we used fMRI to delineate brain response to the onset and offset of unpleasant and pleasant auditory stimuli in the absence of learning or motor response. Increased NAcc activity was seen for the onset of both pleasant and unpleasant stimuli. Our results support the expanded bivalent view of NAcc function and call for expansion of current models of NAcc function that are solely focused on reward.

publication date

  • February 1, 2009

has subject area

  • Acoustic Stimulation
  • Adult
  • Auditory Perception
  • Brain Mapping
  • Female
  • Humans
  • Male
  • Motivation
  • Nucleus Accumbens
  • Reward

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2659952

Digital Object Identifier (DOI)

  • 10.1016/j.neuroimage.2008.09.039

PubMed ID

  • 18976715

Additional Document Info

start page

  • 1178

end page

  • 1187

volume

  • 44

number

  • 3