Impact of molecular staging methods in primary melanoma: Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) of ultrasound-guided aspirate of the sentinel node does not improve diagnostic accuracy, but RT-PCR of Peripheral blood does predict survival
Reverse Transcriptase Polymerase Chain Reaction
Sentinel Lymph Node Biopsy
US-FNAC is highly accurate and eliminates the need for SLNB in 16% of all SLNB patients. RT-PCR of the aspirate or excised SN does not improve sensitivity or specificity. RT-PCR of blood samples predicts DFS and OS.