NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Apoptosis
  • Camptothecin
  • Cell Proliferation
  • Prostatic Neoplasms

abstract

  • The data obtained suggest that NSC is able to decrease cell growth, induce cell apoptosis and cause growth arrest in prostatic tumor cells, which may involve an interaction with topoisomerase 1 and an activation of mitochondrial apoptotic pathway.

publication date

  • January 2009

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3960998

Digital Object Identifier (DOI)

  • 10.1007/s00280-008-0740-8

PubMed ID

  • 18373093

Additional Document Info

start page

  • 303

end page

  • 12

volume

  • 63

number

  • 2