Mucosal cytokine imbalance in irritable bowel syndrome Academic Article uri icon

Overview

MeSH Major

  • Cytokines
  • Intestinal Mucosa
  • Irritable Bowel Syndrome

abstract

  • Despite the expected heterogeneity of the disorder, differences in mucosal chemokine signalling were evident in this cross-sectional study of IBS patients at the level of both gene expression and protein secretion, with IBS patients demonstrating a consistent deficit in the expression and secretion of chemokines known to play a critical role in mucosal defence.

publication date

  • December 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1080/00365520802276127

PubMed ID

  • 18752146

Additional Document Info

start page

  • 1467

end page

  • 76

volume

  • 43

number

  • 12