A prospective feasibility trial to determine the significance of the sentinel node gradient in breast cancer: A predictor of nodal metastasis location
Sentinel Lymph Node Biopsy
Dye gradients occur in most SNs and predict metastasis location. The smallest metastases are hardest to detect intraoperatively and are usually confined to the marked SN half. This suggests that marking an SN's bluest half warrants further study to explore whether its correlation to metastasis location may be exploited to focus pathologic examination and decrease the reoperative axillary dissection rate.