Gallbladder cancer (GBC): 10-Year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC) Academic Article uri icon

Overview

MeSH Major

  • Gallbladder Neoplasms

abstract

  • GBC is commonly diagnosed incidentally (47%). Re-exploration reveals a high incidence of residual disease (74%). Median survival is better for patients who have no evidence of disease on re-exploration (72 months) compared to those with residual disease detected (P < 0.0001). Overall prognosis is poor. Although we did not observe a survival benefit for those who received adjuvant therapy, the study did not have sufficient power to address this question. In addition, the number of patients who received adjuvant therapy was small with marked heterogeneity in clinical and therapeutic details, precluding any definitive conclusions being drawn. Prospective randomized trials of adjuvant therapy are needed in this disease.

publication date

  • December 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/jso.21141

PubMed ID

  • 18802958

Additional Document Info

start page

  • 485

end page

  • 9

volume

  • 98

number

  • 7