Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial Academic Article Article uri icon

Overview

MeSH Major

  • Acquired Immunodeficiency Syndrome
  • Anti-Retroviral Agents
  • HIV Infections
  • HIV-1

abstract

  • This cell-mediated immunity vaccine did not prevent HIV-1 infection or reduce early viral level. Mechanisms for insufficient efficacy of the vaccine and the increased HIV-1 infection rates in subgroups of vaccine recipients are being explored.

publication date

  • November 12, 2008

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0140-6736(08)61591-3

PubMed ID

  • 19012954

Additional Document Info

start page

  • 1881

end page

  • 93

volume

  • 372

number

  • 9653