Changes in mood states and biomarkers during peginterferon and ribavirin treatment of chronic hepatitis C Academic Article uri icon

Overview

MeSH Major

  • Antiviral Agents
  • Depression
  • Hepatitis C, Chronic
  • Interferon-alpha
  • Polyethylene Glycols
  • Ribavirin

abstract

  • Depression during peginterferon and ribavirin therapy was associated with a lower antiviral response. The significant reduction in whole blood serotonin levels over time suggest that further studies of the serotonergic pathway are warranted to identify the mediators of interferon-induced depression.

publication date

  • November 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3712502

Digital Object Identifier (DOI)

  • 10.1111/j.1572-0241.2008.02106.x

PubMed ID

  • 18721241

Additional Document Info

start page

  • 2766

end page

  • 75

volume

  • 103

number

  • 11