Systemic Therapy for Metastatic Renal Cell Carcinoma Review uri icon

Overview

MeSH Major

  • Carcinoma, Renal Cell
  • Kidney Neoplasms

abstract

  • Renal cell cancer (RCC) is the most common form of cancer of the kidney and accounts for approximately 44,000 cases per year in the United States. Historically, only immunotherapy showed activity in metastatic RCC. The improved survival and quality of life for patients with metastatic RCC over the last several years are direct results of advances made in understanding the development of RCC. Three targeted therapies-sunitinib, sorafenib, and temsirolimus-have been approved for use in the United States recently. Current research is aimed at developing new drugs and combining available drugs to improve upon the responses and survival seen with approved single agents.

publication date

  • November 2008

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2008.07.007

PubMed ID

  • 18992622

Additional Document Info

start page

  • 687

end page

  • 701; ix

volume

  • 35

number

  • 4