Familial and Hereditary Renal Cancer Syndromes Review uri icon

Overview

MeSH Major

  • Kidney Neoplasms
  • Neoplastic Syndromes, Hereditary
  • von Hippel-Lindau Disease

abstract

  • Hereditary and familial forms of kidney cancer are encountered routinely in urologic practice. Discoveries in the genetic and molecular biology of these diseases have had a critical impact on the understanding of kidney cancer pathogenesis in nearly all subtypes of renal cortical neoplasms and their clinical features. Developing knowledge in the field has helped formulate new diagnostic and molecular therapeutic strategies for patients who have kidney cancer. This article aims to familiarize the reader with the current understanding of identified syndromes, their biology, and approaches to treatment.

publication date

  • November 2008

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2008.07.014

PubMed ID

  • 18992610

Additional Document Info

start page

  • 563

end page

  • 72; v

volume

  • 35

number

  • 4