Immunophenotypic analysis of the Kaposi sarcoma herpesvirus (KSHV; HHV-8)-infected B cells in HIV+ multicentric Castleman disease (MCD) Academic Article uri icon

Overview

MeSH Major

  • B-Lymphocytes
  • Giant Lymph Node Hyperplasia
  • HIV Infections
  • Herpesviridae Infections
  • Herpesvirus 8, Human
  • Lymphoma, Primary Effusion

abstract

  • Although both PEL and MCD originate from KSHV-infected pre-terminally differentiated B cells, these findings, with previously reported genetic studies, indicate HIV+ MCD may arise from extrafollicular B cells, whereas PELs may originate from cells that have traversed the germinal centre.

publication date

  • November 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1365-2559.2008.03144.x

PubMed ID

  • 18983461

Additional Document Info

start page

  • 513

end page

  • 24

volume

  • 53

number

  • 5