Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo Academic Article uri icon

Overview

MeSH Major

  • Acyltransferases
  • Antineoplastic Agents
  • Melanoma

abstract

  • Tris DBA is thus a novel inhibitor of N-myristoyltransferase-1 with significant antitumor activity and is well tolerated in vivo. Further preclinical evaluation of Tris DBA and related complexes is warranted.

publication date

  • September 15, 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4423743

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-08-0405

PubMed ID

  • 18794083

Additional Document Info

start page

  • 5743

end page

  • 8

volume

  • 14

number

  • 18