Fractionated doses of ionizing radiation confer protection to mesenchymal stem cell pluripotency
Mesenchymal Stromal Cells
Pluripotent Stem Cells
The authors have demonstrated that even minor alterations in fractionation of radiation dose can result in significant effects on the potential of mesenchymal stem cells to differentiate. These findings imply that at least some of the variability in tissue damage after radiation therapy observed clinically may be attributable to differences in the delivery of ionizing radiation.