Tracking organ overlap for a constrained non-rigid registration algorithm Academic Article uri icon


MeSH Major

  • Brain Neoplasms
  • Radiosurgery


  • This paper tracks organ (prostate, rectum, bladder) overlap in a constrained non-rigid registration (NRR) algorithm to register computed tomographic (CT) images used in external beam prostate radiotherapy. The local motion of the organs is described by a hierarchical multi-resolution FFD based on cubic B-splines. Registration is achieved by minimizing a cost function which is a combination of three functions representing the overlap of the critical organs, image similarity and smoothness of the transformation. The constrained NRR algorithm generated better registration results when compared to an unconstrained NRR algorithm.

publication date

  • September 10, 2008



  • Academic Article



  • eng

PubMed Central ID

  • PMC2814434

Digital Object Identifier (DOI)

  • 10.1109/ISBI.2008.4541207

PubMed ID

  • 20126424

Additional Document Info

start page

  • 1159