Infusion-related reactions to infliximab in patients with rheumatoid arthritis in a clinical practice setting: Relationship to dose, antihistamine pretreatment, and infusion number Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antirheumatic Agents
  • Arthritis, Rheumatoid
  • Diphenhydramine
  • Histamine H1 Antagonists
  • Hypersensitivity

abstract

  • Infusion-related reactions to infliximab were infrequent, rarely severe, and easily manageable. The frequency of reactions was equivalent in patients treated with 3 mg/kg compared to 5 mg/kg. Reactions were significantly more frequent in infusions where patients were pretreated with the antihistamine diphenhydramine, compared to those not involving pretreatment.

publication date

  • October 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 15468353

Additional Document Info

start page

  • 1912

end page

  • 7

volume

  • 31

number

  • 10