Histological and hormonal studies in rats bearing ovarian implants in the spleen. Effects of portacaval anastomosis
Ovaries were implanted into the spleens of ovariectomized rats. Plasma FSH levels increased rapidly after implantation and this was followed by an increase in plasma concentrations of LH. These raised levels were sustained for at least 140 days after operation. Plasma prolactin levels showed no change. Portacaval anastomosis prevented the increases in plasma hormone concentrations, blocked the growth of fresh implants and caused atrophy of established implants. © 1974.
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