High Mobility Group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • HMGA1a Protein
  • Pancreatic Neoplasms

abstract

  • The current findings suggested that HMGA1 is an independent predictor of poor postoperative survival in patients with pancreatic adenocarcinoma. Furthermore, HMGA1 promotes tumorigenicity through a PI3-K/Akt-dependent mechanism. HMGA1 warrants further evaluation as a prognostic marker and therapeutic target in pancreatic cancer.

publication date

  • July 15, 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2997611

Digital Object Identifier (DOI)

  • 10.1002/cncr.23560

PubMed ID

  • 18473350

Additional Document Info

start page

  • 302

end page

  • 14

volume

  • 113

number

  • 2