Macaque model for severe acute respiratory syndrome. Academic Article uri icon

Overview

MeSH

  • Animals
  • Humans
  • Lung
  • Macaca

MeSH Major

  • Disease Models, Animal
  • SARS Virus
  • Severe Acute Respiratory Syndrome

abstract

  • Rhesus and cynomolgus macaques were challenged with 10(7) PFU of a clinical isolate of the severe acute respiratory syndrome (SARS) coronavirus. Some of the animals developed a mild self-limited respiratory infection very different from that observed in humans with SARS. The macaque model as it currently exists will have limited utility in the study of SARS and the evaluation of therapies.

publication date

  • October 2004

has subject area

  • Animals
  • Disease Models, Animal
  • Humans
  • Lung
  • Macaca
  • SARS Virus
  • Severe Acute Respiratory Syndrome

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC521815

Digital Object Identifier (DOI)

  • 10.1128/JVI.78.20.11401-11404.2004

PubMed ID

  • 15452262

Additional Document Info

start page

  • 11401

end page

  • 11404

volume

  • 78

number

  • 20