Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma
Academic Article
Overview
MeSH Major
Disease Models, Animal
Glaucoma
Microglia
Minocycline
Neuroprotective Agents
Optic Nerve Diseases
Retina
abstract
These observations suggest that in glaucoma, retina and optic nerve head microglia activation may be a factor in the early decline in function of the optic nerve and its subsequent degeneration.